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bipolar constant current stimulator  (Digitimer North America LLC)


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    Digitimer North America LLC bipolar constant current stimulator
    Bipolar Constant Current Stimulator, supplied by Digitimer North America LLC, used in various techniques. Bioz Stars score: 96/100, based on 3326 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/bipolar+constant+current+stimulator/DS3+Constant+Current+Stimulator/pmc12705067-194-18-22
    Average 96 stars, based on 3326 article reviews
    bipolar constant current stimulator - by Bioz Stars, 2026-09
    96/100 stars

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    Isolation:

    Article Title: Differences in nerve excitability properties across upper limb sensory and motor axons.
    Article Snippet: Objective: The excitability of motor and sensory axons of the main upper limb nerves were compared to characterise the differences between nerves and provide a guide for future studies in human diseases with median neuropathy at the wrist.. Methods: Axonal excitability studies were undertaken on median and ulnar motor (APB and ADM) and sensory axons (D2 and D5) and the superficial radial axons (D1) using a threshold tracking technique.. Results: Compared to the median, ulnar motor axons had reduced early depolarising threshold electrotonus (TEd40(10–20 ms) p = 0.02) and superexcitability (p = 0.03).

    Article Title: Dissociable memory modulation mechanisms facilitate fear amnesia at different timescales
    Article Snippet: .. The US was a mild electrical shock delivered to the right wrist of participants via a DS- 5 Isolated Bipolar Constant Current Stimulator (Digitimer, Welwyn Garden City, UK). ..

    Article Title: Dissociable memory modulation mechanisms facilitate fear amnesia at different timescales
    Article Snippet: .. The US was a mild electrical shock delivered to the right wrist of participants via a DS-5 Isolated Bipolar Constant Current Stimulator (Digitimer, Welwyn Garden City, UK). ..

    Article Title: Axonal excitability as an early biomarker of nerve involvement in hereditary transthyretin amyloidosis.
    Article Snippet: .. An isolated linear bipolar constant current stimulator (DS5, Digitimer, Welwyn Garden City, UK) provided the stimuli, and the motor or sensory compound action potential was amplified by a purposebuilt low-noise preamplifier (Howells et al. 2018); gain: 250 for motor recordings, and 10 k for sensory recordings; bandpass filter, 2 Hz – 2 kHz). ..

    Article Title: Serum electrolyte concentrations and skeletal muscle excitability in vivo.
    Article Snippet: Objective: Multi-fibre muscle velocity recovery cycle (MVRC) assessment is a well-tolerated method of evaluating sarcolemmal excitability in vivo that shows promise as a research tool and biomarker.. MVRC parameters correlate with venous electrolyte concentrations in myopathies.. We sought to determine the nature of any such relationships in individuals without muscle disease.

    Article Title: Potassium channel dysfunction and distinct sensory axonal profiles in painful type 2 diabetes.
    Article Snippet: Objective: This study aims to characterize sensory axonal changes in patients with non-painful and painful type 2 diabetes mellitus (T2DM) to explore the mechanisms underlying diabetic neuropathic pain in relation to pregabalin treatment.. Methods: Clinical evaluations, including nerve conduction studies, nerve excitability testing (NET) and visual analogue scale (VAS), were conducted on 200 T2DM, resulting 131 qualifying for inclusion.. Cohort stratification utilized VAS scores: 43 had VAS ≥ 4 (painful), and 88 had VAS < 4 (non-painful).

    Article Title: Long-interval afferent inhibition measurement using two different methods: Normative values, repeatability and reliability.
    Article Snippet: Background: The mechanism of Short-Latency Afferent Inhibition (SAI) is relatively well understood.. In contrast, Long-Latency Afferent Inhibition (LAI) has not been as extensively studied as SAI, and its underlying mechanism remains unclear.. Objective/Hypothesis: This study had two primary objectives: first, to determine the optimal ISIs for LAI measured by amplitude changes (A-LAI) using high-resolution ISI ranges; and second, to compare measurements of LAI by threshold-tracking (T-LAI).

    Amplification:

    Article Title: Axonal excitability as an early biomarker of nerve involvement in hereditary transthyretin amyloidosis.
    Article Snippet: .. An isolated linear bipolar constant current stimulator (DS5, Digitimer, Welwyn Garden City, UK) provided the stimuli, and the motor or sensory compound action potential was amplified by a purposebuilt low-noise preamplifier (Howells et al. 2018); gain: 250 for motor recordings, and 10 k for sensory recordings; bandpass filter, 2 Hz – 2 kHz). ..

    Software:

    Article Title: Potassium channel dysfunction and distinct sensory axonal profiles in painful type 2 diabetes.
    Article Snippet: Objective: This study aims to characterize sensory axonal changes in patients with non-painful and painful type 2 diabetes mellitus (T2DM) to explore the mechanisms underlying diabetic neuropathic pain in relation to pregabalin treatment.. Methods: Clinical evaluations, including nerve conduction studies, nerve excitability testing (NET) and visual analogue scale (VAS), were conducted on 200 T2DM, resulting 131 qualifying for inclusion.. Cohort stratification utilized VAS scores: 43 had VAS ≥ 4 (painful), and 88 had VAS < 4 (non-painful).



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